2016 Finalists

Organization Organization Location Project
Kenya Medical Research Institute (KEMRI) Migori County, Kenya

Across the developing world, data on neonatal mortality and morbidity are inaccurate, as there are very few opportunities to capture this information once a newborn leaves the facility. We propose to pilot an interactive communications platform, mThrive, which will enable families and the healthcare community to exchange vital information during the critical window of development up to one year. mThrive will provide parents with health education messages and ask diagnostic questions to identify infants needing targeted follow-up.

mThrive: A Mobile Health Education and Survey Platform to Track Newborn Outcomes to 28 Days and Beyond
Asociación de Investigación, Desarrollo y Educación Integral Quetzaltenango, Guatemala

Guatemala has some of the worst maternal-child health (MCH) statistics in the world, with indigenous often faring 2-3 times worse than the non-indigenous populations, likely due to a history of political, economic and social exclusion. Gender inequality and violence, poor social support and emotional distress directly impact pregnancy outcome.

Leveraging Individual and Collective Resilience to Improve Perinatal Health Outcomes in Marginalized Communities of Guatemala
Becton, Dickinson and Company Franklin Lakes, New Jersey, USA

Gestational Diabetes Mellitus (GDM) is the most common complication of pregnancy and pre-eclampsia (PE) is a top cause of maternal mortality. In India, 12-15% of pregnancies are impacted by GDM.

Introduction of Innovative, Biomarker-based POC Testing for Preeclampsia and Gestational Diabetes in India
Bempu Health Private Limited Bengaluru, Karnataka, India

Preterm babies often suffer from apneas. In low-resource settings where nurses are few, these apneas can often go unnoticed or detected late, which could lead to irreversible injury to the newborn. APNEBOOT is a shoe-shaped apnea monitor which alerts in the event of an apnea. In the event of apnea, it also stimulates the foot which could be life-saving in the case of central apneas and absence of a caretaker.

Development and Validation of APNEBOOT to Detect And Stimulate In The Event Of Apnea Of Prematurity In Low-Resource Settings.
Bloodworks Seattle, Washington, USA

Bloodworks proposes a “just-in-time” solution for blood transfusion, a Bloodpak, to prevent maternal mortality from obstetrical hemorrhage in low-resource settings.   The Bloodpak is an on-demand blood donation and transfusion system, consisting of rapid point-of-care tests to identify safe volunteer blood donors, a clinical guide on a smart phone application to provide decision support during the interve

Bloodpak: A Civilian Walking Blood Bank Model to Prevent Maternal Mortality from Obstetrical Hemorrhage in Remote and Austere Settings
Burnet Institute Melbourne, Victoria, Australia

Burnet will develop a simple, lateral-flow point of care test that can identify white blood cell changes that have been well-validated as markers of neonatal sepsis, but have previously required complicated flow cytometry for evaluation. This technology development will facilitate future manufacture and worldwide distribution of a validated test to reduce death and disability from neonatal sepsis. The objective and end point is a validated test that can be transferred to manufacture and clinical trials for maximum impact.

Going Against the Flow: Diagnosis of Neonatal Sepsis at the Point of Care
Cornell University Ithaca, New York, USA

South and Central America are currently experiencing a rapid epidemic of Zika infection, which may be associated with an increase of newborn microcephaly cases in Brazil. With elevated concerns for pregnant women, an accurate and deployable ZIKV diagnostic is a global health priority. This proposal seeks to develop a rapid and portable Zika infection diagnostic device to detect both ZIKV RNA and human antibodies against ZIKV.

ZikaPhone: Point-of-Care Diagnosis of Zika Virus Infection
D-Tree International, Inc. Boston, Massachusetts, USA

The Safer Deliveries project will improve the ability of nurses and midwives to identify danger signs for a woman and her baby during the critical period of labor and delivery and link these measures to specific decision support rules that guide the health worker in taking corrective action.

Safer Deliveries Using Point of Care Decision Support and Monitoring
Fundação Oswaldo Cruz Rio de Janeiro, Brazil

Up to 2% of babies born alive in LMICs suffer neonatal encephalopathy (NE), accounting for one million deaths per annum Millions of survivors are permanently affected. A lasting solution is critical. Therapeutic Hypothermia (TH) is by far the most potent neuroprotectant: several randomized clinical trials have confirmed TH’s safety and efficacy in improving outcomes.

Rethinking Therapeutic Hypothermia on Neonatal Transport: A Highly Effective and Low Cost Sustainably Focal Brain Device
Future Generations Franklin, West Virginia, USA
Customarily, mothers are taught health lessons which, even if simplified, are paradigmatic and hard to remember. This project advances a proven method that transforms the training of community health workers (CHW), leading to faster progress in knowledge and behavior change of mothers who learn from older women whom they know and trust.
Life narratives are how women naturally communicate.
Women Sharing Personal Narratives to Change Health Behaviors at Scale
Harvard T.H. Chan School of Public Health Boston, Massachusetts USA

Mounting evidence suggests that utilization of low-quality facilities is a major contributor to poor maternal and newborn outcomes in Kenya. Kenya’s Ministry of Health is increasingly prioritizing policies to improve the quality of facility-based maternal and newborn care and promote high quality facilities. This proposal is to develop a novel report card tool to provide pregnant women with essential information on the technical quality of local maternity facilities.

Choosing Quality: Can Facility Report Cards Promote Utilization of High Quality Maternal Care in Nairobi, Kenya?
Health-E-Net Limited Nairobi, Kenya

There are large gaps in the quality of documentation of maternal and newborn health data and in the use of these data to identify and mitigate risk factors in pregnancy and childbirth. Health-E-Net has developed clinical documentation tools that bridge traditional paper-based interfaces with electronic medical records.

PaperEMR: Paper-Based Interface to an Electronic Medical Record System to Improve Point-of-Care Documentation and Quality of Maternal and Newborn Health Services Delivered at In-Patient and Out-Patient Facilities in Low-Resource Settings
Jhpiego Baltimore, Maryland, USA

Postpartum infection is a leading cause of maternal mortality (11% globally and 8% in Uganda), yet management approaches have not changed in 30 years. While women are more commonly delivering in hospitals, overcrowding results in their early departure.

Finalization and Validation of a Postpartum Screening Tool Focused on Identifying Risk Factors for Maternal Infection as Part of Routine, Pre-Discharge Service Delivery
JSI Research & Training Institute, Inc. Boston, Massachusetts, USA

Community based interventions have been shown to significantly reduce maternal illnesses, pregnancy complications and perinatal and neonatal deaths. However stock outs of critical commodities have also been shown to lead to deaths of millions of women and children during pregnancy and birth in low-income countries.

Replicating cStock: Making Essential Health Commodities Available at the Community Level
Living Goods San Francisco, California, USA
Six million children die each year from preventable diseases such as malaria, diarrhea, and pneumonia. While low-cost, life-saving tools exist, more than one billion people lack access to a health worker. Volunteer community health workers (CHWs) with basic health training are the first and only link to health care for millions of people. However, few CHW platforms have proven their impact or reached scale.
Scaling a Proven, Innovative Community Health Worker Model in Uganda
Magee-Women's Research Institute Pittsburgh, Pennsylvania, USA

The pregnancy complication preeclampsia is the second leading cause of maternal death worldwide, accounting for nearly 80,000 maternal deaths and approximately 500,000 infants deaths each year. The vast majority of maternal and infant deaths as a result of preeclampsia occur in low and middle-income countries. This is a science and technology proposal. We are proposing a randomized, double blind, placebo controlled trial of the nutraceutical L-citrulline to decrease the incidence of preeclampsia.

Citrulline Trial to Prevent Preeclampsia
Massachusetts General Hospital Boston, Massachusetts, USA
As demonstrated in the findings that have emerged from our Round 4 Saving Lives at Birth Seed Grant, maternal and newborn death and disability due to obstructed labor and lack of access to other emergency and essential reproductive health operations/procedures can be reduced with increased availability of surgical services through invoking our innovative package, Every Second Matters for Mothers and Babies - Ketamine (ESM-Ketamine).
Scaling up Every Second Matters for Mothers and Babies - Ketamine (ESM-KetamineTM) in Kenya
Massachusetts General Hospital Boston, Massachusetts, USA

Every Second Matters for Mothers and Babies–Obstetric Fistula™ (ESM–OF™), includes a best-evidence package of training in prevention, recognition and repair (using beef tongue and pig anus models for novel simulation), a checklist, and a repair kit, accompanied by the development of specific policies that, together, will allow for elimination of unrepaired third- and fourth-degree obstetric tears at the community level. 

Every Second Matters for Mothers and Babies – Obstetric Fistula (ESM-OF)
MAZA Greater Accra, Ghana

MAZA is establishing a transportation network in rural Ghana that is multi-purpose, affordable, accessible and reliable to meet urgent health care transportation needs. In the remote areas of Ghana, sick people trying to urgently get to hospital face prohibitive obstacles such as long distances, impassable roads, few motorized vehicles, unreliable transportation service, and insufficient funds. This is one of the primary root causes of the urban/rural disparity in premature deaths in Ghana, especially for pregnant women and infants.

MAZA - Transportation Saving Lives in Rural Ghana
Monash University Melbourne, Victoria, Australia

Over 300,000 women die each year due to pregnancy-related causes with hemorrhage being the leading cause. Oxytocin is the gold standard therapy to prevent postpartum hemorrhage and is recommended by the WHO to be used at every birth. Oxytocin is currently available as an injection that requires refrigeration to maintain quality and skilled healthcare workers to safely administer the product. These factors significantly limit the availability and impact of this medicine, particularly in resource poor settings.

Inhaled Oxytocin: Bringing Gold Standard Postpartum Hemorrhage Prevention to Women in Greatest Need
Muso San Francisco, California, USA
The leading killers of pregnant women and newborns progress and kill rapidly. Yet people living in extreme poverty face multiple delays to care, many of which occur before patients even reach the door of a clinic. Most health care in the world is passive – doctors and CHWs wait for patients to come to them. Muso has designed a health care system optimized for speed, which saves lives by reaching patients early. A Harvard/UCSF study documented a 10x increase in access to care and a 10x difference in under-five child mortality after the rollout of the Muso model in an area of Mali.
Testing a Scalable Model to Save Millions of Lives
Novate Medical Technologies New Orleans, Louisiana USA

Novate Medical Technologies is a medical device development company committed to addressing the health needs of the developing world. Novate’s first product, InfaClip, is a non-reusable obstetric device that simultaneously cuts and clamps the umbilical cord, focused on addressing neonatal mortality due to umbilical cord infections while reducing unintended blood borne pathogen exposure during the birthing process.

Novate Medical Technologies: Infaclip is an Obstetric Device that Simultaneously Cuts and Clamps the Umbilical Cord While Reducing Exposure to Unintended Blood Borne Pathogens
Open Development, LLC Washington, DC USA

As the universal health coverage movement grows, most countries cannot rely on public providers alone to meet the increased demand for health services. Engaging private providers in maternal and neonatal care can improve healthcare access and quality and reduce out of pocket spending among the poor. Yet the maternal and newborn episode of care (EOC), which begins with antenatal visits, includes delivery and postpartum care, and ends in postnatal consultation, is one of the more complex health coverage conditions.

The Maternity Episode of Care Prototype (Liberia)
Oxford University Oxford, United Kingdom

Neonatal and maternal emergencies are major causes of death. However, any one health worker, especially in primary care or community settings, will provide an emergency response infrequently. Face-to-face learning costs between $80 to $300 per day and only a small fraction of health workers have access to this. New strategies are therefore required to improve access. Using serious games should enable health-workers to follow and learn highly structured care pathways (or algorithms). Key information (cues) is sought at each step that determines correct actions.

Life-saving Instruction for Emergencies (LIFE) Delivered Using Serious Games and mHealth Technologies
Partners in Health Boston, Massachusetts, USA

To address maternal and neonatal mortality in Lesotho, Partners In Health (PIH) piloted a project that increased facility-based delivery from 5% to 95% with zero institutional maternal deaths over 2 years. With this experience, PIH and the Ministry of Health (MOH) initiated a district-driven healthcare reform in 2014. Modifications made to the pilot model for national scale-up (i.e., an initial focus on supply-side health systems strengthening interventions alone) have not produced facility-based delivery rates needed to reach targeted mortality reductions.

Empowerment and Accountability: Building District-Level Leadership of Health Care Reform in Lesotho
PATH Seattle, Washington, USA

The WHO estimates that preeclampsia (PE) accounts for at least 16 percent of maternal deaths in low-resource settings (LRS). Due to its high cost and complexity, the reference standard for proteinuria diagnosis, 24-hour urine collection, is largely unavailable in antenatal care (ANC) in LRS. Instead, the standard of care for proteinuria detection for the majority of pregnant women in routine ANC is the low-cost, but inaccurate protein-only dipstick test.

Field Validation of a New Protein-To-Creatinine (PrCr) Strip Test: An Impactful New Tool to Improve Diagnosis of Preeclampsia at the Front Lines of Antenatal Care in Low-Resource Settings
PATH Seattle, WA, USA

Neonatal sepsis is a major cause of infant mortality in low-resource areas. While intramuscular antibiotic treatment regimens have been shown to be effective and safe, access to these treatments are limited to areas serviced by higher level healthcare workers, trained and approved to administer injections to infants. We propose to investigate the feasibility of a needle-free method of administration for the antibiotic gentamicin via the rectal route.

Outpatient Treatment of Neonatal Sepsis by the Rectal Administration of Gentamicin
PATH Seattle, Washington, USA

Sepsis is a leading cause of neonatal mortality, often due to missed diagnoses, delays in care-seeking, and lack of access to trained health care providers (HCPs). This project uses approaches the improvement of the management of bacterial infection by developing a mobile platform, the Rapid Integrated Sepsis risk-Calculator (RISC), which will assist HCPs to quickly identify sick infants and treat or refer those at highest risk of death.

Early Recognition and Management of Severe Sepsis in Newborns: a Rapid, Integrated Approach
PATH Seattle, Washington USA

In obstetric and newborn emergencies, infusion pumps are used to provide safe and accurate delivery of lifesaving medications, fluids, and nutrition. In low-resource settings (LRS), this standard of care is often not available due to unreliable electricity and the prohibitive price of the device and costs associated with consumables and training.

Development and Evaluation of the RELI Delivery System—an Innovative, Simplified, Low-Cost Infusion Pump for Obstetric and Newborn Emergencies
Queen's University Belfast Belfast, United Kingdom

In this project, the team will develop a microarray patch to expand lifesaving coverage of vitamin K prophylactic treatment for newborns. This affordable and effective innovative solution will help ensure that this simple, proven treatment for newborn bleeding disorders is available, accessible, and used in all birth settings.  This innovative microarray technology can enable transdermal delivery of many drugs that are not feasible to deliver by other methods.  Dissolving microarray patches are made from a biocompatible polymer system that is hard when dry.

Vitamin K Microarray Patch for Newborns to Avoid Bleeding
Queen's University Belfast Belfast, United Kingdom

An easy-to-use, combined form of amoxicillin and gentamicin could benefit the approximately 10% of infants who show symptoms of possible serious bacterial infection during the neonatal period.  Use of microarray patches for other indications have shown promise in clinical trials. Microarray patches for vaccine applications in particular have been advanced for use in low-resource settings due to the anticipated low cost, ease of use, safety, and stability of the technology.

Microarray Patch for Delivery of a Combination of Antibiotics for the Treatment of Neonatal Sepsis
ResilientAfrica Network, Makerere University School of Public Health Kampala, Uganda

Infections, including those affecting the umbilical cord are a significant factor in approximately a third of the nearly 4 million neonatal deaths, yearly. For the first time in Sub-Saharan Africa, our study will evaluate the effect on these infections and deaths of a single low-cost application of 4% chlorhexidine (CHX) on the umbilical cord stump.

Acceptability and Efficacy of Umbilical Cord Cleansing with a Single Dose of 4% Chlorhexidine for the Prevention of Newborn Infections in Northern Uganda: A Randomized Controlled Trial
Sanguina, LLC Atlanta, Georgia USA

Anemia, or low blood hemoglobin (Hgb) levels, remains a leading cause of maternal and newborn deaths in low resource settings (LRS) where the standard test, a complete blood count (CBC), is cost-prohibitive. This lack of a simple, inexpensive, yet accurate anemia test remains a major issue that prevents the timely detection needed to curtail anemia-associated perinatal mortality. To that end, Sanguina has developed a disposable, color-based test for anemia detection in which the different colors correlate with Hgb levels.

Pilot Testing of a Disposable, Visual, Color-Based Anemia Test for Pregnant Women and Newborns
Sanyu Research Unit, University of Liverpool Liverpool, United Kingdom

Short supply of medications, theatres, and blood transfusion contribute to postpartum hemorrhage (PPH) deaths in low-income countries. Skilled birth attendants may face PPH with limited support or referral options. Bimanual compression of the uterus (between a hand on the abdomen and a fist in the vagina) can be a life-saving treatment; but it is used rarely as it is painful, invasive and tiring to perform.  The PPH Butterfly is an innovative device designed to allow easy, less-invasive uterine compression, whilst facilitating diagnosis of the cause of PPH.

The PPH Butterfly for Life: Development of an Acceptable, Reusable, Cost-Effective and Scalable Tool to Manage Postpartum Hemorrhage in Low-Income Countries.
Sattva Medtech Private Limited Bengaluru, Karnataka, India

10 million mothers are prone to risk factors like anemia, gestational diabetes, hypertension and malnutrition. Their babies are vulnerable to birth asphyxia, fetal acidosis, meconium aspiration syndrome and obstructed labor which is presented by fetal distress during labor. These mothers are serviced by Auxiliary Nurse Midwives (ANMs) in secondary healthcare centers. The ANMs face difficulties in identifying high risk mothers during antenatal scans and especially during labor.

Validation of the Sattva Fetal Lite Device to Prevent Intrapartum Deaths Caused by Fetal Distress and Underlying Complications.
Save the Children Federation Inc. Westport, Connecticut, USA

The evolving WHO guidelines for case management of pneumonia and serious bacterial infections in neonates, infants, and children under 5 years old require community and facility health workers to measure and assess various vital signs for which they have limited tools and often rely on subjective measures, leading to under diagnosing and over prescribing antibiotics. Overlapping disease symptoms make it difficult for health workers to confidently triage an infant or child.

An Affordable and Robust Diagnostic Platform for Neonates and Young Children in Low-Resource Settings
Song Diagnostic Research LLC Menlo Park, California, USA

No inexpensive point of care means for detection HIV in infants born to infected mothers is currently available. Newborns are not candidates for HIV testing using conventional rapid tests targeting anti-HIV antibodies due to the presence of maternally derived antibodies in newborn blood. The reliability of testing for viral protein (p24) is substantially compromised by the formation of immune complexes that shield the target protein from interaction with test reagents.

A Rapid Diagnostic Test for HIV in Infants
Telluride Medical Solutions, Inc. Telluride, Colorado USA

Titratable infusion of oxytocin is needed to induce and stimulate labor and hence minimize maternal mortality, neonatal morbidity and unnecessary Cesarean sections. Titratable infusions are also needed to treat patients, including neonates, in shock. Current infusion methods require expensive electronic pumps, inexact systems using intravenous drip systems or manually counting drops falling into a drip chamber. Telluride Medical Solutions has patented and is developing an inexpensive purely mechanical infusion pump designed for use in low resource settings.

A Low Cost Mechanical Medical Infusion Pump
The University of Chicago Chicago, Illinois, USA

Infectious diseases are the premier causes of neonatal and childhood death in low-income countries (3.257 million cases), as newborns do not receive vaccinations due to limited resources and skilled labor. This project use a science and technology approach to address this problem by developing a safe, temperature-stable attenuated spore-vaccine (ASV) platform for oral administration.

Oral Vaccines for Maternal and Neonatal Health
The University of Sydney Sydney, New South Wales, Australia

Severe infection is the 2nd leading cause of neonatal mortality in Pakistan. Breastfeeding helps protect infants from infections due to multiple anti-infective and immunoregulatory factors including lactoferrin. A trial in Italy found that sepsis and sepsis-related deaths were significantly lower in very low birth weight (LBW) infants who were given daily bovine lactoferrin (bLF) compared to a placebo. A trial from India found a 79% reduction in infections in newborns weighing less than 2000g who received daily bLF from birth until 28 days.

Evaluating the Approach to Administration and Dose of Bovine Lactoferrin to Prevent Neonatal Infections in Low Birthweight Newborns in Pakistan
Universidad Peruana Cayetano Heredia Lima, Peru

The Peruvian Amazon's Loreto region has maternal and neonatal mortality rates nearly twice the national average. Loreto mothers have basic prenatal knowledge, but often do not seek care due to personal and cultural barriers and poor quality of care. To tackle this issue, community members used mobile devices and proven participatory methods to design a digital story curriculum addressing local barriers to prenatal care, safe delivery, and newborn care.

Nuestras Historias: Evaluating the Impact of Community-Created Digital Stories to Motivate Mothers, Partners, and Health Post Workers to Improve Maternal and Newborn Outcomes in the Peruvian Amazon- A Cluster Randomized Trial
University of British Columbia Vancouver, British Columbia, Canada

Postpartum hemorrhage (PPH) is the leading cause of maternal death, killing ~130,000 women per year. These cases occur mostly in resource-limited settings, because of a lack of access to effective interventions. Effectively managing PPH requires a combination of interventions, such as uterine massage, uterotonics, manual uterine evacuation and uterine balloon tamponades (UBT). Even with these interventions, 4% of PPH cases still result in death due to bleeding (~0.25% of all births).

Treating Postpartum Hemorrhage with a Low-Cost Intrauterine Formulation of Tranexamic Acid
University of Iowa, College of Public Health Iowa City, Iowa, USA

One of the primary barriers to obtaining skilled obstetric care is a delay in care-seeking, which is caused by (1) a lack of recognition of risk during labor by the mother and her caregiver(s) and (2) a lack of support from family members during pregnancy and delivery, especially the husband (or male partner).

Home-based, Pictographic Decision-making Tool to Expedite Obstetric Care-seeking Among Low-literate Women and Their Families in Rural Bangladesh
University of Manitoba Winnipeg, Manitoba, Canada

To decrease maternal and newborn mortality women and newborns require improved access to quality evidence based interventions that can be delivered both in the community and the facility. The potential for community health workers (CHWs) to increase access, reduce inequities and improve key reproductive, maternal and newborn health  indicators in rural settings is well recognized.

Applying an Innovative Community and Facility Based Mentoring Model to Improve Quality, Delivery and Utilization of Reproductive, Maternal and Newborn Health Interventions along the Continuum of Care in Pakistan
University of Melbourne Melbourne, Victoria, Australia

One of the reasons oxygen therapy is not reaching the many thousands of babies and children it could save is due to the fact that electricity is not always available in small health facilities. To address this problem, this team has successfully developed FREO2, an electricity-free oxygen concentrator which runs on the energy from water flowing in a nearby stream, and which requires no fuel. It is independent of supply chains and transport infrastructure and has negligible environmental impact.

Validation Study of an Electricity-free Oxygen Concentrator in Western Uganda.
Vanderbilt University Nashville, Tennessee, USA

In this technology development project, the team at Vanderbilt will utilize technological innovation to develop a high sensitivity platform for inexpensive, portable, electricity-free diagnosis of early infant infection at the point of care. Around the world, the expansion of clinical management and life-saving ART into low resource settings has outpaced advances in necessary support infrastructure.

Detection of HIV Infection in Infants Using High Sensitivity HIV-p24 Antigen Detection Technologies
William Marsh Rice University Houston, Texas, USA

There is international consensus that syringe pumps are an essential medical device to support care of mothers and newborns at district hospitals. Yet, they are often unavailable in low-resource settings because of high cost, technical complexity, and lack of brand name consumables. The project’s idea is to scale AutoSyp, a low cost, low power, syringe pump in maternity and neonatal wards of hospitals in Malawi. Designed to work with all brands of syringes, AutoSyP costs 10 times less than other alternatives.

An Accurate, Rugged and Low-Power Syringe Pump for Maternity and Neonatal Care in Resource Limited Settings
Yale University New Haven, Connecticut, USA

PremieBreathe addresses the widespread global health problem of neonatal mortality due to respiratory failure. Over one million newborns die each year due to pneumonia, preterm birth and other respiratory-related causes, accounting for 40% of newborn deaths. While life-saving breathing support technologies are widely available in high-income countries, these respiratory aids are not affordable or designed for use in low- or middle-income countries, where the majority of these deaths occur.

Testing and Implementation of Low-cost Breathing Aid for Infants in Tigray, Ethiopia
Zvitambo Institute for Maternal and Child Health Research Harare, Zimbabwe

HIV-exposed uninfected (HEU) infants have higher morbidity and mortality from serious bacterial infections in the neonatal period than HIV-unexposed infants, but current interventions are started too late to be effective. This project approaches this problem with a package of care delivered by community health workers (CHW) from birth, embracing science and technology, service delivery and demand creation.

Reducing Serious Bacterial Infections in HIV-exposed Uninfected Infants in the Neonatal Period Through a Community Health Worker-delivered Package of Care